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Title: At-Home Exercise Regimen for Outcome Benefit in Congestive Heart Failure (AEROBIC)
Status: Completed
Topic: Cardiovascular Health / Endothelial Function*
Funding Source: American Teachers of Preventive Medicine (ATPM)/Centers for Disease Control and Prevention (CDC)
Funding Period: 10/00 –4/04
Study Design: Randomized, Controlled, Prospective Study
Purpose: To determine whether the addition of a home-based exercise program to a chronic disease management program provides an effective and safe means of improving the health and functional status of patients with congestive heart failure (CHF).
Further Study Details: Twenty (20) adult men and women enrolled in this study were assigned to one of two groups: a chronic disease management program or chronic disease management plus exercise. Those in the exercise group received a treadmill for use in their home and supervised exercise instruction by a cardiac rehabilitation exercise specialist. This year-long intervention included routine monthly telephone calls, and assessments at 3, 6 and 12 months.
Findings: The home-based exercise intervention caused a significant change in perceived fatigue between study groups after 6 months of study participation, with the control group feeling less fatigued than the intervention group. After 12 months of participation, there were no significant differences in perceived functional capacity. Home-based exercise was well tolerated and favorably evaluated. This pilot study demonstrated the feasibility of studying home-based exercise in patients with moderate congestive heart failure. Larger and longer studies will be required to determine treatment effects.
Eligibility: Adult men and women with an established diagnosis of CHF.

Changed at: 1/18/2011 5:20 AM Changed by: Judy Treu
Created at: 8/31/2010 9:37 AM Created by: Griffin Hospital